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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Pharmacogenovigilance: Knowledge, Attitudes and Practice Towards Pharmacogenomics, and Pharmacovigilance in Drug Safety Among Final-Year Medicine and Pharmacy Students, Malaysia

Author: DR HAQUE, YAU ADAMU
Abstract: Introduction: The need for adoption of pharmacogenomics and pharmacovigilance into practice among healthcare professionals has been increasing as this provides greener future to individualized medicine and drug safety. Objectives: This study aimed to assess the knowledge, attitude and practice of final-year Medicine and Pharmacy students towards Pharmacogenomics, and Pharmacovigilance in drug safety at some public and private universities in Malaysia. Method: A cross-sectional study was conducted using a self-administered questionnaire (Cronbach's alpha coefficient 0.822) among 463 participants, yielding a response rate of 380 (82.1%) over the period of the study. Data Analysis: The analysis of the continue variables was done using the student t-test and one-way ANOVA. The associations between categorical variables were analyzed using the Chi - square test. Results: More than half (62.6%) were Medicine students and female accounting for 64.74% of all the participants. The majority of the participants has demonstrated high knowledge and attitude scores; Pharmacy students reported to have higher knowledge and attitude scores towards pharmacogenovigilance than medical students with a p=0.001 and <0.001 respectively. However, a low level of practice was observed with significant differences between pharmacy and medicine students (P<0.05). Conclusion: These results showcase the readiness of final-year medical and pharmacy students towards the Pharmacogenomic and pharmacovigilance based challenges, which would help in policy making and educational intervention hence a reduction in drug related problems.
Keyword: Pharmacogenomics, pharmacovigilance, Drug safety, KAP, Pharmacogenovigilance
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