*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *         Journal is Currently Not Indexed in Scopus as on february 2021 list Updated by scopus

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Convenient Method for Synthesis and Purification of N-Desmethylmianserin-An Active Metabolite of Mianserin

Author: UPLOADED BY-ADMIN, CHAUHAN B, VASU KK, SUDARSANAM V
Abstract: N-Desmethylmianserin is a pharmacologically active metabolite of mianserin. A new method was developed to synthesize N-Desmethylmianserin from mianserin using 1-chloroethylchloroformate. This reaction ended with the mixture of N-Desmethylmianserin and mianserin. The N-Desmethylmianserin hydrochloride was separated from starting compound using novel approach of selective derivatization.
Keyword: Mianserin, N-desmethylmianserin, Antidepressant
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