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Pharmacognostical, Phytochemical Screening and Antioxidant Activity of Butea monosperma
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| Author:
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ARTI YADAV, SONIA PANDEY, JITENDRA SINGH YADAV
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| Abstract:
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Objective: The aim of the present research was focused on to study detailed pharmacognosy and in-vivo antioxidant activity of bark. Methods: The macroscopy, microscopy, physiochemical analysis, preliminary testing of powder of the plant and other WHO recommended methods for standardization were investigated. Ethanolic extract of Butea monosperma (Lam.) Taubbark was evaluated for in-vivo antioxidant activity. Results: Trunk bark consists of two distinct regions i.e. outer bark and inner bark. Outer bark consists of broad periderm of a wide phellem and inner phelloderm regions.Inner bark is broader than the outer part and it includes all the secondary phloem tissues. It can be distinguished into collapsed and non-collapsed secondary phloem regions. Collapsed secondary phloem region consist of sclereids and sieve tubes and dilated axial parenchyma cells. Non-collapsed secondary phloem region is consists of intact sieve tube members, companion cells, axial parenchyma cells and narrow undilated ray. Calcium oxalate crystals are abundant in collapsed phloem region. After injecting CCl4, the anti-oxidant activity of various enzymes was noted i.e. Superoxide dismutase, Glutathione peroxidase, Catalase and tissue lipid peroxidation. 200 mg/kg ethanolic extract showed good anti-oxidant activity as compared to silymarin, Conclusions: It can be concluded that the pharmacognostic profile of the Butea monosperma (Lam.) Taub is helpful in developing standards for quality, purity and sample identification. The free radical scavenging activity of ethanolic bark extract of Butea monosperma (Lam.) Taub showed good activity as compared to standard.
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| Keyword:
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Butea monosperma Lam. Taub., Pharmacognostic; Morpho-anatomy; periderm, anti-oxidant activity
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| DOI:
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