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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparison Efficacy of Amygdalus Scoparia and Pumpkin Seed Oil in Treatment of Benign Prostatic Hyperplasia

Author: MOJDEH DAVOODI, AMIR MEHRABI, SADROLLAH MEHRABI
Abstract: Aim of this study is comparing the effect of Amygdalus scoparia and pumpkin seed oil in treatment of symptoms of benign prostatic hyperplasia. In this randomized clinical trial, men older than 45 years old with benign prostatic hyperplasia with an IPSS score of less than 20 were randomly assigned in two groups. In the first group, 20 drops of pumpkin seeds oil was prescribed every 12 hours for 1 month. In the second group, the Amygdalus scoparia in dose of 2 g / day was prescribed as a herbal tea for one month. In both groups 0.4 mg of tamsulosin was taken as standard treatment every night. Patients in both groups were checked before and after taking the drug and their IPSS were recorded. The data were analyzed using SPSS software version 18 and statistics tests including mean and standard deviation, paired t-test and Chi-square. Results showed that Mean score of IPSS in two groups before intervention was not significant (P = 0.520). However, the mean scores of IPSS after intervention were significantly different in two groups and this mean in the Amygdalus scoparia group (7.6 ± 1.3) was lower than the pumpkin seed oil group (8.7 ± 1.88), P = 0.002). Also, intra-group comparisons after intervention was showed that mean scores of IPSS significantly decreased in both groups.in conclusions this study showed that both herbal tea of Amygdalus scorparia and pumpkin seed oil reduces the symptoms of benign prostatic hyperplasia, although the effect of Amygdalus scoparia is more significant.
Keyword: Benign prostate hyperplasia, symptoms, herbal remedy, mountain almond (Amygdalus scoparia), pumpkin seed oil.
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