IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit


For More Detail Visit ncsp.ganpatuniversity.ac.in
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPRT ISSUE

January - March 6 [1] 2014

Click to download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
FORCED DEGRADATION STUDY OF POST-SHELF LIFE AND MARKETED TABLETS OF ZOLMITRIPTAN BY RP-HPLC

Author: DR.VIDYASAGAR CHANDRAMANAIDU, C.SRINIVASULU
Abstract: The stability of pharmaceutical products plays an important role from the economic point of view. There are not many studies that report about the stability of drugs past their expiration dates. The objective of the current study was to determine the tablet content of expired tablets of Zolmitriptan where expiry date has not exceded and to develop simple,accurate,sensitive and stability indicating RP-HPLC method for the determination of per cent drug remained of Zolmitriptan in the presence of its degradation products in bulk drug,expired tablets and tablets whose expiry date has not been exceeded.Drug was subjected to all stress conditions such as hydrolysis(acidic and alkaline),oxidation,photolysis,thermal degradation and humidity study.Content determination was performed using RP-HPLC method,the per cxent of dissolved substance from tabletswas also performed.All stressed samples were successfully analysed on C18 column using mobile phase acetonitrile: methanol: 0.1% orthophosphoric acid 69:29:2 (v/v/v) mobile phase (pH5.1).A flow rate was maintained at 1.5 Ml/mim and detection was made at 210nm.The proposed method was validated with regard to linearity,sensitivity and accuracy and precision.No discrepencies between the results of determination and the declared values range for all the analysed tablets were observed.The results of performed study might suggest that storage of analysed batches of tablets over time period exceeding the expiry date given by the manufacturer did not influence their contents
Keyword: Zolmitriptan,Stability,Expired Tablets,RP-HPLC
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
Pharmacovigilance: Current Scenario and Emerging Trends

National Conference sponsored by GUJCOST on 03.08.2019 at SNLPCP, Umrakh

Download Brochure
News & Events
0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus
Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477