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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Phytochemical and pharmacological studies of stem bark of Cordia myxa Roxb extract

Author: RASHMI MALLYA, MANISHA OZA, PADMINI RAVIKUMAR, MADHAVI APTE
Abstract: Cordia myxa Roxb (Boranginaceae) commonly known as Lasura is a middle sized tree widely growing in warmer parts of India. The plant is mentioned in Ayurveda as Sleshmataka and its various parts are used in folklore medicine. Traditionally,this plant is used as an anthelmintic, astringent, diuretic, demulcent, expectorant and tonic. It is also used for treatment of ulcers and snake bites. The present investigation deals with phytochemical evaluation and study of in-vivo anti-inflammatory and wound healing activities of hydroalcoholic extract of stem bark of Cordia myxa on rats. The preliminary phytochemical screening on the extract revealed the presence of carbohydrate, phenols, tannin, sterols and saponins. The total phenolic content and total tannin content per gm of bark extract was found to be 93.1 ± 0.2 mg gallic acid equivalent and 66.34 ± 0.3mg tannic acid equivalent respectively. It also exhibited significant wound healing activity when applied topically within a duration of 16 days. Also,remarkable anti-inflammatory activity of (80%) at the end of 6 hours on carrageenan induced raw paw edema was attained. These activities could be attributed to the polyphenols present in the stem bark extract.
Keyword: Cordia myxa, wound healing, anti-inflammatory, polyphenols.
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