Synthesis and fungicidal activity of substituted 1-[(1,3-dioxolan-4-yl)]methyl-1H-imidazoles and 1-[(1,3-dioxolan-4-yl)methyl]-1H-1,2,4-triazoles based on arylidene ketones
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Author:
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V.S. TALISMANOV, S.V. POPKOV, O.G. KARANOVA, S.S. ZYKOVA
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Abstract:
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Chloromethyldioxolanes were synthesized on the basis of arylidene ketones obtained by condensation of ketones
with aldehydes. The interaction of chloromethyldioxolanes with 1,2,3-triazole or imidazole resulted in the substituted
1-[(1,3-dioxolan-4-yl)]methyl-1H-imidazoles, 1-[(1,3-dioxolan-4-yl)methyl]-1H-1,2,4-triazoles.In vitro tests of
substituted compounds showed high fungicidal activity against six common fungal phytopathogens: Sclerotinia
sclerotiorum, Fusarium oxysporum, Fusarium moniliforme, Bipolaris sorokiniana, Rhizoctonia solani and Venturia inaequalis.
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Keyword:
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alkylation, 1,3-dioxolane, imidazole, fungicidal activity, ketalization, ketals, 1,2,4-triazole.
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2019.11.02.051
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