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The Effect of Percutaneous Coronary Intervention on Cerebral Blood Flow
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| Author:
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HUSSEIN NASER, AHMED M H , NAJAH H R, AEDAH F IBRAHIM, MUHDI E MUHDI
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| Abstract:
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Background and aim of the study:Ischemic heart disease is now the leading cause of death worldwide.It has been
expected that the mortality rate of coronary artery disease will be increased in the developing
countries.Percutaneous coronary intervention (PCI) provides an effective symptomatic treatment. Cerebral blood
flow constitutes about 14% of resting cardiac output. The aim of the study is to see the effect of percutaneous
coronary intervention on cerebral blood flow status.The study was conducted at Al Sader Medical City in Najaf City
during the period from April 2017 to March 2018. Cerebral blood flow of bilateral middle cerebral artery was
measured before and day14 after percutaneous coronary intervention by Trans cranial Doppler (TCD) in 32 patients
eligible for study .The left ventricular ejection fraction also measured by transthoracic echocardiography at same time
of TCD examination.There was a statistically significant increase in the ejection fraction value after PCI compared to
its value before PCI with a mean difference of 1.7 ± 1.3, (P< 0.001). The TCD parameters; peak systolic velocity
(PSV), end diastolic velocity (EDV) and mean flow velocity (MFV), all are increased significantly after PCI. The changes
in plasticityindex (PI) and resistive index (RI) were reduced from its baseline value before PCI. There was a positive
correlation between the changes in middle cerebral artery (MCA) flow velocity with the changes in ejection fraction.
Percutaneous coronary intervention significantly increases cerebral blood flow through an increase in middle cerebral
artery (MCA) flow velocity and a decrease in its resistance.
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| Keyword:
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percutaneous coronary intervention, cerebral blood flow
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.02.034
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| Download:
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