*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Risk Factors Associated with Recurrence of Tuberculosis at the Chest Clinic, Hospital Raja Perempuan Zainab II Kota Bharu Malaysia

Author: DR HAQUE, MYAT MOE THWE AUNG, NYI NYI NAING, ABDULLAH MOHAMED RUSLI, MAT JAEB MAT ZUKI, NADIAH WAN-ARFAH, MAINUL HAQUE
Abstract: Introduction: Tuberculosis (TB) was the disease with the second highest incidence rate and caused the highest mortality rate among communicable diseases in Malaysia. Current study wants to identify the associated factors of recurrence among TB patients. Methods: A retrospective record review study of 114 patients registered as recurrent TB cases attending the Chest Clinic of Hospital Raja Perempuan Zainab II (HRPZ II), Kelantan, Malaysia within January 2003 to December 2009 were conducted. The Cox Proportional Hazards Regression analysis was used. Results: After adjustment of other potential confounding variables, the alcoholism (adjusted Hazard ratio [aHR]: 24.53, 95% CI:1.96,306.29), the sputum smear result at the initial diagnosis of previous occurrence of TB (aHR: 4.09, 95% CI:1.52,11.02) were more likely to have recurrent TB whereas the treatment regimen with twice weekly doses of Streptomycin (S), Isoniazid (H) and Rifampicin (R) drugs (S2H2R2) during the continuation phase (aHR: 0.11,95% CI:0.02,0.54)was found as a significant protective factor for recurrent TB. Conclusion: The recurrent TB cases can be reduced by treating the patients with S2H2R2 drug regimen during the continuation phase while we must be aware of hazards of recurrent TB for alcoholics and patients with positive sputum smear result at the initial diagnosis of TB.
Keyword: Tuberculosis, Recurrent, Protective Factor, Cox Proportional Hazards Regression Analysis, Malaysia
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free