IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Assessment of ZnO Nanoparticles Effect on Peroxidase Activity in Serum of Patients with Type2 Diabetes Millets : in vitro study

Author: ZAINAB SALMAN, SABREEN A.MEZIL, VEAN S. ALI, NADIA M.KADIM
Abstract: Nanoparticle applications have been improved in different areas of sciences, among these are the medical applications. In did , the estimation of their effects in this field can be evaluated via studying of their effects on the relevant biochemical functions of the investigated disease. The aim of this study is to estimate the effect of ZnO nanoparticles on peroxidase activity in serum of patients with Type2 Diabetes Millets. Serum samples of 30 patients, aged (40-60) years, with type2diabetes millets were collected as a patients group. Control group included 20 samples were obtained from 20 healthy subjects, aged (40-60). Nanoparticles of ZnO were used in this study in a diameter less than 80 nm. Serum peroxidase activity of the studied groups was estimated in absence and presence of ZnO Nanoparticles by colorimetric method. The obtained results in this study were showed that the activity of serum peroxidase in presence of ZnO NPs in patients group was lower than its activity in this group without ZnO NPs. at the same time, both its activities in patients group (with and without ZnO NPs) were found to be lower than its activity in control group. This study show decreasing of serum peroxidase activity in presence of ZnO NPs. this effect may be due to the biological activity of this type of NPs in addition to the conformational changes that can be occurred on the protein structure .
Keyword: Serum, Peroxidase , Diabetes Millets , ZnO NPs.
DOI: https://doi.org/10.31838/ijpr/2019.11.02.014
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0.12
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0.07
2017CiteScore
 
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477