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Polymorphism of IL-1ß gene in Iraqi pediatric pneumonia patients
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| Author:
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EMANMOBDERNAYIF FRIAL, GEMEELABD
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| Abstract:
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A Patients -healthy specimens were collected between February 2017-May 2017 and its included 100 Iraqi patients
infected with pneumonia that diagnosed by consultant physician and 30 specimens of healthy control group from
Babylon Province two types of specimen have be taken from each subject in present study first: blood samples for
DNA extraction from WBCs, second: serum samplesfor estimation the concentration of IL-1ß by ELISA
technique.Enzyme –linked immunosorbent assay technique showed that the concentration of IL-1 ß in serum patients
have non-significant increase (p = 0.108) in comparison with healthy control,79.1960± 24.88416pg / ml for patients
and43.9806± 92.47785 for healthy control group.According to SNPs-genotypes combination principle the pneumonia
patients have genotype CT-CT and TT-TT .While the healthy control has CC-CC genotype. find the relationship
between pneumonia and polymorphism of IL-1and its concentration in serum.
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| Keyword:
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SNP , polymorphism, IL-1 ß, pneumonia, ELISA
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.02.010
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| Download:
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Request For Article
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