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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Expectant Management of Sever PRE-Eclamsia: Maternal and Neonatal Outcome

Author: MASOUMEH MIRZAMORADI, SORAYA SALEHGARGARI, PARICHEHR POORANSARI, MAHBOOBEH GHARIBLAKY
Abstract: Background and aim: Preeclampsia is a multisystem, highly variable disorder unique to pregnancy and a leading cause of maternal and fetal/neonatal morbidity and mortality. The objective of the present study was to compare the benefits and risk of interventional and expectant management in women with Preeclampsia, which is more beneficial by comparing the maternal and neonatal outcome. Methods: 220 women were enrolled in the study, 63 women in the intervention group due to contraindication (cause of termination of pregnancy) and divided into three groups. (28-30w, 30-32w and 32-34w). The conservative treatment group (157), which lasted more than two days from admission to termination of pregnancy, was transmitted to the department after the initial assessment, depending on the amount of blood pressure and laboratory abnormalities. Then maternal and fetal complications were compared in two groups of intervention and conservative treatment. Statistical analysis of collected data were done using IBM. SPSS statistics software 23.0 Version. Result: women age mean was 31.45 (4.59) between 20-41. Maternal condition dictated termination of pregnancy in the expectant management more commonly than fetal condition. Though maternal complications were slightly higher with the expectant management (15% vs. 8%), but it was not found to have statistical significance (p value 0.919). These complications were well managed by multidisciplinary care, indicating institutional supervision of expectant management. The most frequent maternal complication in both the group was abruption, followed by eclampsia (3.8%) in expectant management. Conclusion: Expectant management of preterm severe preeclampsia results in a better obstetric outcome
Keyword: pre-eclampsia, maternal, neonatal, expectant management
DOI: https://doi.org/10.31838/ijpr/2019.11.01.132
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