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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Effect of Aspirin and Clopidogrel on C-Reactive Protein in Acute Ischemic Stroke

Author: MUFEED TAHA, AHMED SHAKIR SHUKUR
Abstract: Stroke is considered as one of major causes of disability and subsequent death. This study aimed to assess one of vascular marker 'C-Reactive protein' response with usage of antiplatelet aspirin vs. clopidogrel in Kirkuk city. A prospective follow-up study was achieved in Kirkuk city in Medicine and Neurology department of Azadi Teaching Hospital starting at 1st February 2018 ending to 1st December 2018, included 60 acute stroke patients. It had been found that there is an acute elevation of CRP blood levels in both aspirin and clopidogrel treated groups in acute ischemic stroke patients and fall on subsequent months. In conclusion, that there is no statistical significant difference between prescribing of aspirin or clopidogrel treatment for acute ischemic stroke patients on CRP blood levels, as well known that CRP is one of prognostic markers , so usage of aspirin or clopidogrel as monotherapy in secondary prevention had same prognostic value.
Keyword: Acute ischemic stroke, Aspirin, Clopidogrel, C - reactive protein.
DOI: https://doi.org/10.31838/ijpr/2019.11.01.122
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