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Study of LD50 and chronic toxicity of suspension of Silver nanoparticles size 50 nm in laboratory rats
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| Author:
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NINO CHICHIVEISHVILI, TEIMURAZ TAVKHELIDZE, SALOME KHUBULAVA, GIORGI PITCHKHAIA, JENARA KRISTESASHVILI, DAVIT KACADZE
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| Abstract:
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Antibiotic era is coming to the end, becouse of the wrong selecting of antibiotics and combination therapy and the
mutation skills of bacteria. In recent years, the use of nanosilver particles for therapeutic purposes has become more
relevant. These particles have an antibacterial effect and a fairly good effect on local inflammatory processes. We
made suspension of silver nanoparticles size 50 nm by the physic method and introduced into laboratory rats. Our
studies demonstrates that argentium nano-particles can be administered in physical (non-chemical) pathways. It does
not have LD50, however, its consumption with high doses for prolonged period of time leads to histomorphological
changes in healthy tissues.
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| Keyword:
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silver nanoparticles, Drug toxicity.a
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.01.121
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| Download:
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Request For Article
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