IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Synthesis and biological evaluation of a series of new pyrimidine-thione as potential antimicrobial agents

Author: RANA ATIYA, NAJI M ALI, EMAD ABBAS JAFFAR AL-MULLA
Abstract: This study was involved synthesis of new 2-Arylakylthio-5-halo-6-methyl pyrimidine-4(3H)-one derivatives. The structure of the target compounds were confirmed via (FT-IR,1HNMR and 13C-NMR spectral studies). The pharmacological activity of all of the synthesized compounds toward bacteria inhibition Staphylococcus aureus (Gram positive bacteria) and Escherichia coli (Gram negative bacteria) was tasted and compared with the references Benzyl penicillin and toward fungal inhibition Candida albi cans also was tested and compared with the reference Fluconazole. The antibacterial results of some of the synthesized compounds shown promising results and some derivatives have activities similar of the references used. The anti-fungal results of the synthesized compounds show promising results in comparison with references drug.
Keyword: Pyrimidine derivatives, Antibacterial, Anti-fungal activity
DOI: https://doi.org/10.31838/ijpr/2019.11.01.085
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2017CiteScore
 
11th percentile
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477