IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit


For More Detail Visit ncsp.ganpatuniversity.ac.in
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPRT ISSUE

January - March 6 [1] 2014

Click to download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Anti-carcinogenic and cytotoxic effect of Carthamus oxycantha Safflower seed oil extract on Hela cell lines

Author: MUHAMMAD AL-SARHAN, LAITH MOHAMMED JAWAD AL-SHAMAA
Abstract: The current study investigates theeffect of plant abstract of Wild Safflower(Carthamasoxycantha) on Hela cell (cancer cell) that thought it works as anticancer drugs. Thesamples of theCarthamasoxycanthaare taken from thewest desert of Iraq while Hela cell supply by Iraqi Biochemistry company.Carthamasoxycanthauses asoily and aqueous extraction,anditsuses in many of different concentrations (eight concentrations) (7.81, 15.62, 31.25, 62.5, 125, 250, 500, 1000) µg /ml for each extract, and for 24,48, and 72 hours of exposure time. The final results show a gradually cellular toxic effect of extracts on Hela cell lines growth. Also, there are some differences in the effect of these extracts based on the extracts concentration and the time. The cytotoxic effect of the extracts kills 50% of cells (CC50) for each extract.Furthermore, we found the aqueous extract most potent cytotoxic extracts on Hela cell than oily extract. HeLa cells were the most sensitive to high concentrations, whatever the concentration increase; it will inhibitthe Hela cell more. Active compounds such as Triterpene concreted in flower, oleic acidandlinoleic acidhaveantitumor activity. As concluding, Carthamasoxycanthaextracts (aqueous or oily) have a great role in inhibition of cancer growth.
Keyword: The plant abstract, Carthamasoxycantha, Hela cell line.
DOI: https://doi.org/10.31838/ijpr/2019.11.01.047
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
Pharmacovigilance: Current Scenario and Emerging Trends

National Conference sponsored by GUJCOST on 03.08.2019 at SNLPCP, Umrakh

Download Brochure
News & Events
Google Scholar

hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus
Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477