IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit


For More Detail Visit ncsp.ganpatuniversity.ac.in
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPRT ISSUE

January - March 6 [1] 2014

Click to download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
The Inhibitory Efficiency of Flavonoid Extract of Black Mustard Seeds (Brassica nigra) and cold aqueous extract of Euphorbia prostrata L. on growth of Staphylococcus aureusinvitro and invivo

Author: HANAN NOURI
Abstract: The aim of this study is to evaluate the antibacterial activity for flavonoids extract for Brassica nigra and cold equeous extract for Euphorbia prostrata plants on growth of Staphylococcus aureus in vitro and in vivo. Six bacterial species were isolated and identified from different conditional cases like enteric infection, diarrhea and skin abses. These are Staphylococcus aureus (36.52%), Escherichia coli ,(44.34%), Bacillus cereus (4.34%), Klebsiellapneumoniae (6.08%), Pseudomonas aeruginosa (15.65%) and Proteus mirabilis (2.60%). The results showed that flavonoid extracts from Brassica nigra is highly active in inhibition than cold equeous extract from Euphorbia prostrata, the inhibitory effect appear to be at a concentration of (25) mg/ml for the flavonoids extract and there is an increase in diameter of inhibition zones with the increase of conc. While the cold equeous extract at (75) mg/ml conc seem to be active on growth at Staphylococcus aureus only. MIC values were determine to be at (50,70) mg/ml for flavonoid extract on Staphylococcus aureus and Escherichia coli respectively and (80,90) mg/ml for cold equeous extract on the same bacteria.The value of LD50 for cold equeous extract was (1383) mg/kg and for flavonoids extract(2500) mg/kg in mice. Also this study proved that the animals infected with Staphylococcus aureus when injected with cold equeous extract of what showed no activity in vivo and died after (2) days of treatment while the animals injected with flavonoids extract gave high activity for Staphylococcus aureusinvivo in (250,300) mg/kg, with clinical symptoms through maintaining the normal values of blood and showed no clinical symptoms after injecting the animals with the flavonoids extract and bacteria, while animal injected with bacteria alone produced changing in blood values and developed clear clinical symptoms ended with the death of animals.
Keyword: Brassica nigra , Euphorbia prostrata L. , invitro , invivo ,Staphylococcus aureus.
DOI: https://doi.org/10.31838/ijpr/2019.11.01.046
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
Pharmacovigilance: Current Scenario and Emerging Trends

National Conference sponsored by GUJCOST on 03.08.2019 at SNLPCP, Umrakh

Download Brochure
News & Events
Google Scholar

hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus
Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477