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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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SAM (Saponin Anti Mosquitoes) - Biolarvicide activity of Rambutan (Nepheliumlappaceum) towards Mosquito Larvae

Author: JAMAL H, FARZANA Y, NAJNIN A, RASHID MA, KARIM AJ, DEEPTHI S, NAZMUL MHM
Abstract: SAM is an innovation of the saponin as a larvicide bioactive from rambutan (Nepheliumlappaceum) seeds and rinds against the larvae of mosquito, the transmitters of several public health problems. SAM contains active ingredient saponin to control mosquito larvae in aquatic habitat. The seeds and the rinds of rambutan, which are normally discarded, were found to contain saponin. The purpose of this project was to optimize the utilization of natural saponin from rambutan seeds and rinds in mosquito control to create biolarvicide as an alternative to the use of Temephos (trade name: Abate) as mosquito larvicides. Natural saponin offer an advantage over synthetic larvicide as this is less prone to development of resistance and easily biodegradable. Besides, this project aims to provide a cheap and efficient alternative of mosquito control system to the mass produced by chemical substances used today. Experiments to extract saponin from the seeds and rinds of rambutan as well as to test the effect of saponin extract on mosquito larvae were conducted to produce the best larvicide product. The best concentration of saponin on larvae biological activity was also determined. The contributions of this project are considerably great as many people out there are suffering from dengue. SAM is relatively low-cost and affordable to wide range of poor communities affected by these diseases. Hence, the use of saponin as a biolarvicide will definitely benefit all of mankind due to its efficiency, while still maintaining its eco-friendly status.
Keyword: SAM, Saponin, rambutan, larvicide, Nepheliumlappaceum
DOI: https://doi.org/10.31838/ijpr/2019.11.01.033
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