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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Phytochemical screening and antimicrobial studies on the leaves of Calotropis gigantea

Author: RAMADEVI BANKAPALLI, SITA KUMARI KARANAM, AV.S.K.BHAVANI
Abstract: The methanolic and petroleum ether extracts of Calotropis gigantea leaves were screened for phytochemical screening. Alkaloids, glycosides, flavonides, saponins, resins and phenols etc. were detected in the leaves extract fractions. The leaves extract of C.gigantea were also screened for antimicrobial activity. The extracts were tested against Gram positive bacteria, Gram negative bacteria such as Staphylococcus aureus & Escherichia coli and fungi such as Aspergillus niger & Mucor using agar well diffusion method. Both the extracts showed significant antimicrobial activity. The petroleum ether extract of C.gigantea showed more antimicrobial activity against Staphylococcus aureus than methanolic extract. The methanolic extract of C.gigantea showed more antimicrobial activity against Escherichia coli than petroleum ether extract. The results confirmed that presence of antifungal and antibacterial activity in the leaf extract of C.gigantea against the human pathogenic organisms.
Keyword: Calotropis gigantea, leaf, phytochemical screening, antimicrobial activity.
DOI: https://doi.org/10.31838/ijpr/2019.11.01.019
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