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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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THE EFFECTIVENESS OF DRY PROBIOTIC IN THE TREATMENT AND PREVENTION OF SALMONELLOSIS

Author: NINA GAVRILOVA*, IRINA ALEXANDROVNA RATNIKOVA, KUANYSH BAYAKYSHOVA, NURSHAT MARATOVNA UTEGENOVA, RAUSHAN ZHUMABEKOVNA KAPTAGAI
Abstract: A comparative study of the treatment-and-prophylactic efficacy of probiotic in the sublimation-dried form as compared to the liquid one against salmonellosis in experimental rabbits has been carried out. A high therapeutic activity of the probiotic used in the experiment has been established both in combination with antibiotic and without it. The disease of rabbits was mild, their rapid recovery was noted, and the transition from the acute form of the disease to the chronic one was prevented, which has been confirmed by bacteriological studies. However, in some cases, the dry drug had an advantage over the liquid one due to the higher content of biologically active substances therein. The best result was obtained when treating salmonellosis and pasteurellosis in rabbits, simultaneously receiving antibiotics in combination with probiotic. Prolonged administration of probiotics by experimental rabbits protected them from salmonella infection.
Keyword: probiotics, salmonellosis, prevention, treatment, animals.
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