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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis and In-vitro Anthelmintic Activity of Some 4-aminophenol Derivatives

Author: UPLOADED BY-ADMIN, VIVEK DANIEL, KRATIKA DANIELA, SWAPNIL GOYALB, MAHENDRA S.PARIHARC, MANGAL SINGHA
Abstract: Some new 4- amino phenol Derivatives were synthesized, to begin with compound methyl 2-(4- aminophenoxy)acetate was synthesized which on treatment with various amines like morpholine, dimethyl amine,diphenyl amine and diethyl amine gave the target compounds. Structures of the synthesized compounds were established on the basis of Melting Point, TLC, IR, NMR and MASS spectral data. The anthelmintic activity of the synthesized compounds was evaluated by Passive avoidance test.
Keyword: 4-Amino phenol, methylchloroacetate, Amines, Potasium Carbonate, Ethyl methyl ketone, earthworm,paralysis, Albendazole, wormicidal, Anthelmintic activity, and Passive avoidance.
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0.12
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