*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Molecular-based identification of spermatogenesis quality improvement within two weeks induced by combination of intense exercise and cinnamaldehyde in Wistarmale rats fed high fat diet

Author: WAFAA ABDULLAH
Abstract: Exercise, low fat diet, or supplementations alone could show improvement in spermatogenesis quality afterlong period of times that could reach up to months especially in males who have high access to a high fat diet (HFD), so the current work was generated to induce this improvement in less amount of time, ~ 2 weeks, using intense exercise and cinnamaldehyde in Wistar male rats (WMR) fed an HFD. To initiate the experiment, 40 WMRs(fed an HFD for 4 weeks before the exposure to the experimental variables (EEV) and continued after that) were randomly divided into 4 groups in which a group received intense exercise and cinnamaldehyde (IECd), a group exposed to cinnamaldehyde alone (Cd), another group subjected to intense exercise alone (IE), and a group given the carrier of CD (CrCd). The EEV was lasted for 2 weeks, and the animals were subjected to measuring serum testosterone (ST), sperm counting (SpC) of motile and viable sperms, and inducible nitric oxide synthase (iNOS) gene expression (iNOSge) using real time-polymerase chain reaction (RT-PCR).The levels of the ST and SpC of motile and viable sperms were significantly (p<0.05) increased in the IECd group when compared with those in the Cd, IE, and CrCd groups. No differences (p>0.05) were noticed between Cd, IE, and CrCd groups when tested for the levels of ST and SpC. The iNOSge levels were significantly (p<0.05) decreased in the IECd group when compared with those in the Cd, IE, and CrCd groups. No differences (p>0.05) were noticed between Cd, IE, and CrCd groups when tested for the levels of iNOSge. This study indicates important effects of the intense exercise and cinnamaldehyde when applied together in improving the quality of spermatogenesis in Wistar rats that could be tested in the future on the human model.
Keyword: Cinnamaldehyde, high fat diet, intense exercise, spermatogenesis.
DOI: https://doi.org/10.31838/ijpr/2018.10.04.101
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free