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ASSESSMENT OF WOUND HEALING ACTIVITY OF VARIOUS ANTIBIOTICS PRESCRIBED IN THE IN-PATIENT UNITS OF ORTHOPEDICS DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL
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| Author:
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MR. KUMAR, MS. C. PRIYA BHARATHI, MS. G. SUDARSINI TRYPHEENA, MS. K. O. VAISHALI, MS. K. SRAVYA, DR. KONDE ABBULU
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| Abstract:
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Orthopedics wounds are defined as the traumatic wounds due to h ard and/or soft tissue trauma. Infec tion in orthopedics wound is one of the m ost dismay obs tacles and is allied with prolonged morbidity, disability & increased mortality. Hence, antibiotics are mos t commonly and frequently prescribed drugs for long peri ods in orthopedics departm ent. In many instance s election of anti biotic also depends on the evidence gathered by orthopedics surgeons throughout th eir clinical practice. In this study we aimed to measure the effectiveness of various antibiotics prescribed either as per recomm endations or evidence based in management of various orthopedics wound in a tertiary care teaching hospital. A six month prospective case seri es analysis study was conducted in Orthopedics Department, Gandhi hospital, Secunderabad with approval from Institu tional Ethical commit tee, CMR College of Pharmacy and from Orthopedic department. S tatistical outcom e of results was obtained using Analysis of variance (ANOVA). A total of 115 cases were included and analyzed, of the 6 documented diagnosis; closed fractures and open fractures had high incidence. Total 17 antibiotics were prescribed for 365 times, with Cefotaxime, Cefuroxim e and Amikacin being most frequent. A minor deviation was also found betw een prescribed and recommended antibiotics. But overall effec tiveness from antibioti c was significant in uplifting the patient care as there was no reported Advers e Drug Reaction (ADR) and length of s tay (LOS) was appropriate in terms of orthopedic wound management. Further, choice of drug also falls within the very guidelines in the coll ected cases and only few number of wound infection .
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| Keyword:
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Orthopedics, Wound healing, Antibiotic, Effectiveness.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2018.10.04.057
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| Download:
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