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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Olfactory assessment of sweat samples of people with diseases of different etiologies

Author: K.YU ZUBRIKOVA, A.V BEDAREVA, N.A LITVINOVA, L.V CHERNISHOVA
Abstract: To study the ability of a person to recognize the smell of people of the opposite sex, infected with STIs, viral infections and allergic diseases. Sweat from underarms and saliva was collected from 80 men (from 18 to 35 years) belonging to 4 groups: 1 - healthy men; 2 - men who are often ill with ARI; 3 - men diagnosed with syphilis; 4 - men with a diagnosis of "gonorrhea"; 5 - men who have allergic diseases. Then, the smell of sweat samples was evaluated by 107 healthy young women (18 to 23 years old). Concentrations of cortisol, testosterone, secretory immunoglobulin A (IgA) and immunoglobulin G (IgG) were measured in saliva by immune-enzyme analysis. The most attractive samples were the smell of healthy men and men diagnosed with syphilis. It was revealed that the infectious status of men was not related to the level of hormones and immunoglobulins in saliva. Presumably, the causative agent of syphilis Treponema pallidum is characterized by an evasion of the immune response due to the unusual molecular and biochemical structure of the bacterium. Perhaps, the immune-dependent decrease in the attractiveness of the smell of sick people is part of the evolutionary mechanism that provides unconscious avoidance of a risky sexual partner. Mechanisms of immune defense, not a parasite, lead to a change in odor recognized by the relatives as a signal to rejection.
Keyword: human smell, venereal diseases, Treponema pallidum
DOI: https://doi.org/10.31838/ijpr/2018.10.04.075
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