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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The Combined Effect Study of Herbal Extract (Aloe Vera, Astragalus fasciculifolius and Olive Leaves) on Second-Degree Burn Wounds in Male Rat

Author: ARSALAN AZIZI, HOSSEIN KAVYANI*, HAMID GHAFFARIAN, MOHAMMAD ZOLADL
Abstract: Background: Medicinal plants have therapeutic and restorative properties due to the presence of alkaloids, essential oils, flavonoids, tannins, terpenoids, and saponins. Plants cause wound healing and have antimicrobial activity in the wound, which has highly therapeutic importance. The aim of this study was to investigate the effect of Aloe Vera, Astragalus fasciculifolius and Olive combination on second-degree burn wounds in male rats. Methods: This experimental study was performed on 50 adult male mice in the year 2012 for two control and test groups. After a burn injury in the desired location, combined hydroalcoholic herbal extract was used. In test group, an ointment was applied to the ulcer in the rat daily. In control group, the wounds were washed only with physiological serum. At the end of treatment day, the ulcers were examined for appearance and recovery. The data was analyzed using Kruskal-Wallis and Analysis of variance (ANOVA) tests. Results: The effect of herbal extracts in the intervention group on accelerating the recovery time and the ulcer shape and size was greater than the control group and showed a significant interaction effect, ??<0.5 , between the test and control groups. Conclusion: The use of herbal extracts listed in this study has more significant role than the use of physiological compounds on burn wounds.
Keyword: Herbal Compounds - Burn - Mouse.
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0.12
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