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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Bioactivity Study of Kombucha Black tea and Kombucha with Skim Milk on Some of Physiological and Biochemical Parameters in Male Albino Rats

Author: FAHAD AL-DULAIMI*, WIJDAN I.A. ABD-ALWAHAB, ABEER S. HASAN
Abstract: Kombucha is known as a probiotic, and used in several products to promotions of food. The present research was aimed to determine and investigate the beneficial and protective effects for the beverage of kombucha black tea alone and with skim milk fermented on concentrations of serum glucose, total lipids profile and body weights in male albino rats. The animals were distributed into four groups, the control group (I), group of skim milk (II), kombucha black tea group (III) and Kombucha in skim milk fermented group (IV), the dose of materials under study administered orally for experimental groups by gastric gavage method once daily for period (21) days. Blood samples were collected at the final of experiment and analyzed. The results revealed a significantly higher (p<0.05) in levels of serum glucose, total lipid profile, and significantly decrease (P<0.05) in HDL-C, AST and ALP in the skim milk group (II) in comparison with control group. While, animal groups that treated with Kombucha black tea (III) and Kombucha in skim milk fermentation (IV) lead to significantly decrease in concentrations of serum glucose, total lipid profile, ALT, AST, ALP and significantly higher in HDL-C and body weights in comparison with group (II) and normal control group consecutively. Moreover, administrated of Kombucha in skim milk fermentation showed significant decrease in above mentioned parameters compared with groups which treated with Kombucha black tea only. The obtained present results demonstrate that use Kombucha as a probiotic in skim milk fermented and with black tea lowers the harmful lipids, glucose and aminotransferases in blood, and it's maybe have a beneficial effects on the liver and the health of human body.
Keyword: Kombucha, Total lipid profile, Glucose, Probiotics, Skim milk.
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