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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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LOCAL THERAPY OF CHRONIC RECURRENT APHTHOUS STOMATITIS (CLINICAL-ANDBIOCHEMICAL ASPECTS)

Author: E.V.SHCHETININ, A.V.MIKHALCHENKO, N.I.BYKOVA, MIKHALCHENKO D.V.
Abstract: The Chronic Recurrent Aphthous Stomatitis (CRAS) is often described in practical work of the dentist [9,10,12, 13]. The disease wavy, sometimes with a frequent recurrence which severity and duration increase depending on prescription of a disease proceeds. Sometimes CRAS takes a permanent course. The problem of its treatment remains urgent [1,2,3,9,13]. The majority of the means of local therapy applied at CRAS are insufficiently effective, they are easily washed away by saliva and do not provide acceleration of an epitelization of the injured mucous membrane of oral cavity in short terms. This fact causes need of constant search for new medicine and its rational combinations [5,6,7,8].It is obvious that for effective damage therapy of oral cavity mucous membrane at CRAS it is necessary to use the medicines and substances allowed for use in medical practice with already known properties (for example, adhesive), as well as to develop and offer the new perspective means having universal properties [4,7,11]. In this regard studying the pathogenetic mechanisms of local therapy for damages of oral cavity mucous membrane of CRAS patients and developing the differentiated principles for this disease treatment, are an urgent problem of modern stomatology.
Keyword: mucous membrane, treatment, healing, stomatitis
DOI: https://doi.org/10.31838/ijpr/2018.10.04.040
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