*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *         Journal is Currently Not Indexed in Scopus as on february 2021 list Updated by scopus

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Development and evaluation of polyherbal ointments for anti-inflammatory therapy

Author: JITENDRA YADAV, DR. BIREN N. SHAH
Abstract: In the present investigation, the aqueous and methanolic extracts are screened for its anti-inflammatory activity and the effective dose is used to formulate ointment using different ointment bases. The methanolic and aqueous extracts of Lagenaria siceraria reduced the carrageenan induced rat paw edema by 37.50 % and 62.50 % respectively on oral administration of 200 mg / kg body wt. The methanolic and aqueous extracts of Ocimum gratissimum reduced the carrageenan induced rat paw edema by 61.25 % and 36.25 % respectively on oral administration of 100 mg / kg body wt., while the methanolic and aqueous extracts of Moringa oleifera reduced the edema induced by carrageenan by 60.00 % and 33.75 % respectively on oral administration of 600 mg / kg body wt., as compared to the untreated control group. Diclofenac sodium at 100 mg / kg body wt. inhibited the edema volume by 75.00 %. All the formulation were screened for its anti-inflammatory potential. TSF-3 showed most-significant activity by reducing 66.67 % edema at 4th hour, while TSF-1, TSF-2 and TSF-4 showed 55.56 %, 59.26 % and 37.04 % reduction in paw edema respectively, as compared to the untreated control group. The standard drug inhibited the edema volume by 74.07 % (p<0.05).
Keyword: Moringa oleifera, Ocimum gratissimum, Lagenaria siceraria, Anti-inflammatory activity, carrageenan, edema
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free