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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Polyhydroxybutyrate (PHB): Biodegradable, Bioplastics Produced by Microorganisms

Author: RAHUL SINGH, S. MOHSIN WAHEED, VIKASH BABU
Abstract: Today plastic materials are part of humanities everyday life and are indispensible for numerous consumer goods and applications. The non-degradable property of synthetic plastic accumulates in the environment, where they create problems for wildlife and their habitats as well as for human populations. Human over population combined with the current lifestyle urges the rational, efficient, and sustainable use of natural resources to produce environmentally friendly, biodegradable plastic materials such as poly-hydroxyalkanoic acids (PHAs), poly-lactic acid (PLA). About 75 genera of gram positive and gram negative bacteria are known to produce PHBs when grown in carbon and nitrogen limited media. Some important examples of PHB producing bacteria are Ralstonia eutropha, Alcaligenes eutrophus, Pseudomonas pseudomallei, E. coli, Halomonas campisalis etc. Degradable property of PHB increased demand for biodegradable plastics whose production may reduce undesirable wastes and emissions. There are some other examples of bioplastic are poly-4-hydroxybutyrate (P4HB), polyhydroxyvalerate (PHV), polyhydroxyhexanoate (PHH), polyhydroxyoctanoate (PHO), which have physical properties similar to polypropylene. This review collects the publication which reported the different bacterial strain and their optimization process as well as scale up studies, which will be helpful for researcher with further information.
Keyword: poly-hydroxyalkanoic acids (PHAs), polyhydroxyvalerate (PHV), polyhydroxyhexanoate (PHH), polyhydroxyoctanoate (PHO).
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