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Effects of Liver Cancer Drugs on Cellular Energy Metabolism in Hepatocellular Carcinoma Cells
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| Author:
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MANU KANTI, SOMNATH ROY, DEBABRATA SAMANTA
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| Abstract:
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Liver cancer is the major cause of death among various types of cancer all around the world. Liver has several
functions such as secretion of bile juice into the intestine for the absorption of the fats, liver is also involved in the
manufacturing of the blood clotting factors that are needed to stop the bleeding. In this paper we have put an effort
to study the effects of drugs which are used for the treatment of hepatocellular carcinoma cells and their influence on
the metabolic pathways, specifically on aerobic glycolysis and oxygen consumption by tumour cells to meet their
energy demand also we have discussed growth tumors with respect to temperature.
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| Keyword:
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ATP depletion, Glycolysis, Hepatotoxins, Hypoglysemic effect, Liver cancer, Mitochondrial inner membrane potential, Oxidative phosphorylation.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2018.10.03.079
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| Download:
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