*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *         Journal is Currently Not Indexed in Scopus as on february 2021 list Updated by scopus

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Identification of Potent Natural Inhibitors against H1N1/A/2009 Virus using In Silico Subtractive Genomics Approach and Docking Technology

Author: RAHUL CHAVAN, PRAMOD SHINDE, KAUSTUBH GIRKAR, RAJENDRA MANDAGE, ABHAY CHOWDHARY
Abstract: The 2009 outbreak of H1N1 pandemic killed the thousands of people from the globe. The subtractive genomics approach was used to find out the potent and unique drug target in H1N1/A/2009. Docking studies were carried using HEX, GOLD, iGEMDOCK and Autodock VINA tools and evaluation was carried out using linier regression models with the binding energy provided by the docking tools using training and testing sets. Allicin and Plumbagin were predicted as the potent multi drug targets against the Neuraminidase, Hemagglutinin and M2 protein channel of H1N1/A.
Keyword: H1N1, Subtractive genomic approach, Drug target, docking studies
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