Estimation of Insulin-Like Growth Factor System in Iraqi Children with Hypothyroidism
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Author:
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, , AMAL RASHEED FARHAN
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Abstract:
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To evaluate IGF-1,IGFBP-3,GH in children with hypothyroidism and to predict dwarfism hypothyroidism in children.
Total of (25) children with hypothyroidism and (20) healthy children were including in the present study. Serum IGF-1,
IGFBP-3 ,growth hormone were measured. Serum IGFBP-1 significantly decrease in hypothyroidism patients when
compare to control (p?0.05). There were a significant difference in Growth hormone and IGF-1 levels when compared
between hypothyroidism and healthy groups (p?0.05).All parameters of IGF-1 system significantly decrease in
hypothyroidism patients the lack in thyroid hormone levels may effected on the growth processing
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Keyword:
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Hypothyroidism , IGF-1, IGFPB-3, GH, dwarfism
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EOI:
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http://eoi.citefactor.org/10.11209/ijpr.10.03.003
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DOI:
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https://doi.org/10.31838/ijpr/2018.10.03.032
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