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Hypolipidemic Activity of Aqueous Flower Extract of Hibiscus sabbdariffaL.inHigh Cholesterol Diet Fed Rats.
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| Author:
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DR. ABBAS, WIJDAN KAMAL NOOR SHALAN ALQRAAWY, METHAK ALSHEMKI, DR.SHAIMAA MAHDI A. JAWAD, ZAHRAA S. AL-KAABY
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| Abstract:
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The hypolipidemicactivity of aqueous extract for flowers of Hibiscussabdariffa L. was evaluated
inhypercholesterolemicrats.Thirty two male adult rats were divided into four groups, each one involved eight rats. First
group fed normal diet (normal group). The second group fed with high cholesterol diet (HCD) and received oral
administration of 2 ml sterile water (control group). the third and fourth groups fed with high cholesterol diet(HCD)
and received oral administration of aqueous extract of flowers of H. sabdariffa, 200 and 400 mg/kg respectively in 2 mL
of sterile water for 21 days. The animals were sacrificed; Biochemical analysis of blood serum were performed for lipid
profile and liver enzymes.The extract induces a significant decrease in serum cholesterol, triglycerides and Bloodlevels of
AST, ALT, ALP. The results concluded that Hibiscus sabdariffaextract aqueous (200, 400 mg/kg) have potent
hypolipidemicactivity inhypercholesterolemic rats
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| Keyword:
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rat ; active ; potent;sabdar;hypolipidemic ;potent.
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| EOI:
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http://eoi.citefactor.org/10.11209/ijpr.10.03
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| DOI:
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https://doi.org/10.31838/ijpr/2018.10.03.029
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| Download:
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