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DEVELOPMENT AND VALIDATION OF HPTLC METHOD FOR THE ESTIMATION OF VASICINE, CURCUMIN AND CUCURBITACIN B IN AN AYURVEDIC FORMULATION: PANCHTIKTA GHRITA.
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| Author:
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SHAH D.*, CHAUHAN B, SATANI B
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| Abstract:
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An upsurge towards the usage of alternative medicines is currently being observed worldwide. India has one of the
richest and most diverse heritages in the world and Ayurveda is an integral part of it. But thestandardization of these
phyto-pharmaceuticals still remains a major challenge. The current study is aimed at standardizing an Ayurvedic
formulation: Panchtikta Ghrita by developing a HPTLC method for the estimation of active markers (Vasicine, Curcumin
and Cucurbitacin B) and its validation using the ICH guidelines.[1]The markers are successfully resolved using the mobile
phase chloroform: methanol (9.5:1) and also a good linear relationship is observed in the regression analysis data of each
marker. The proposed method is accurate and reproducible and can thus be applied for the routine quality control
analysis of the formulation.
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| Keyword:
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Standardization, Panchtikta Ghrita, HPTLC, Vasicine, Curcumin, Cucurbitacin B
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| EOI:
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| DOI:
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| Download:
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