*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Effect of Solvent and Non- Solvent Composition on Physical Characters of Mefloquine Hydrochloride Microsphers

Author: UPLOADED BY-ADMIN, V.A.PATEL, R.S.R. MURTHY, H.V.PATEL, KUNDAWALA AJ
Abstract: Mefloquine hydrochloride (MQH) is considered relatively safe effective antimalarial recommended for prophylaxis and chemotherapy of chloroquine resistant and multidrug resistant falciparum malaria. Malaria kills nearly one million people worldwide mostly in developing countries. In present study an attempt was made to produce ethyl cellulose microspheres of MQH by solvent evaporation method, to see effect of solvent composition on in vitro characterization of microspheres. The prepared Microspheres were investigated for % drug entrapment, particle size and in vitro drug release profile. Particle size ranging from 6.82 ± 0.62µm to 55.58 ± 1.1 µm were obtained with respect to different solvent and non solvent composition as dispersed and continuous phase. From in vitro drug release studies it was observed that the values for t50 and t70 were in range of 5-11 day and 6-15 days respectively.
Keyword: Microspheres, Mefloquine Hydrochloride, Solvent evaporation, Malaria
Download: Request For Article
 
Clients

Clients

Clients

Clients

Clients
ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free