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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Design and development of calamine aloe vera herbal hydrogel: A natural supplement to protect skin

Author: LAVAKESH OMRAY
Abstract: Calamine containing aloe vera herbal hydro gel developed to get its hidden wonderful herbal effect of aloe vera in conjunction of calamine. Formulation seems to offer synergistic effect of calamine and aloe vera for the protection of skin and treatment of skin. Herbal gel was developed using flashy part of aloe vera leaf, hydroxy propyl methyl cellulose, calamine, zinc oxide, glycerin, tartaric acid, and sodium benzoate. In this study, formulations C1, C2, C3 and C4 were developed in different concentration of hydroxy propyl methyl cellulos. All the formulations were evaluated for percentage moisture loss, smoothness, viscosity, pH and presence of microbes. Viscosity and pH of the formulation were major criteria for the selection of developed formulation. Because viscosity offers proper contact and application to the skin and pH is useful parameter for making skin compatible product. Formulation C3 was found to have optimum viscosity for the purpose of handling and application on the skin. pH of the formulation was in the acceptable range. Therefore, formulation C3 considered as developed formulation.
Keyword: Aloe vera, calamine, gel, hydrogel, topical preparation
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