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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

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Article In Press
Biomechanical/biochemical factors contributing to cardiac fibrosis in the heart and engineered cardiac tissue
THE ASSOCIATION AND LINKGAGE OF VARIOUS RETROVIRUSES AND ITS PROGRESSION TOWARDS NEURODEGENERATION
Architecture of Viral RNA Helicases; HCV helicase as Antiviral Target
GC-MS analysis of rhizome extract by Cold maceration of Curcuma amada Roxb.
Development and Evaluation of Febuxostat Sublingual Tablet Formulation
Development and Evaluation of Febuxostat Sublingual Tablet Formulation
A comparative study of adaptogenic effect of Withania somnifera with Mifepristone (a GR antagonist) on chronic stress - induced perturbations in glucose metabolism
In Vitro Anticancer Activity Of Leaves Of Rumex Vesicarius Linn And Symplocos Racemosa Roxb By Trypan Blue Method
PREPARATION AND INVITRO CHARACTERISATION OF ANTIBACTERIAL NANOCAPSULES
Cytotoxic potential of the crude solvent extract of Botryodiplodia theobromae – an endophytic fungi isolated from Catharanthus roseus.
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January - March 6 [1] 2014

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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Article Detail

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A Dietary Pattern including soluble fiber (ß- glucan) reduces prevalence of Metabolic Syndrome: A randomized, parallel group trial

Author: PRAGYA VERMA, PROF.RATAN K SRIVASTAVA, DR.DHARMENDRA JAIN
Abstract: Background: The Metabolic Syndrome (MS) is a cluster of abnormalities that is accompanied by a 2-fold increase in the risk of cardiovascular disease and has become a major public health concern throughout the world. Clinical trials using barley have shown the potential for a 10–15% reduction in LDL-C when it is added to a ‘heart-healthy’ diet. Most researches on soluble fibre (ß-glucan) have focused on oats, whereas barley another excellent source of this type of fibre but has received very little attention compare to oats. Objective: Thus the present study was designed to investigate whether the consumption of barley would reduce the prevalence of metabolic syndrome components. Design: A total of two hundred four men & women with Metabolic Syndrome aged 30–70 years, participated in a randomized parallel group design comparing a diet rich in soluble fiber ß-glucan (Intervention group) with a control diet ( control group)) of similar macronutrient composition but lacking barley. Both diets followed the National Cholesterol Education Program’s Adult Treatment Panel III NCEP (ATP III) STEP-I diet recommendations. The only difference between the two groups was the inclusion of fixed amount of barley food in the step-1 diet. Results: After the three month of active intervention 45.1% of the patients in the intervention group and 30.6% in the control group were no longer fulfilled the diagnostic criteria of metabolic syndrome. Prevalence of hyperglycemia and Hypertriglycerolemia decreased significantly in both the groups but barley diet was associated with a greater reduction in the prevalence of all components. At the end of trial significant difference were observed between the two groups regarding Hypertriglycerolemia and hyperglycemia. p<0.05 Conclusion: The results from this study suggested that barley intake has beneficial effects on risk factors for CVD. Therefore intake of a high-fiber food especially soluble fiber (ß-glucan) should be strongly recommended to prevent the burden of chronic diseases.
Keyword: Metabolic syndrome, cardiovascular risk factors, barley ß-glucan, Soluble fiber.
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News & Events
22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit https://ncsp.ganpatuniversity.ac.in
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)