IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 1.55 (2012 - 2016). 

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit


For More Detail Visit ncsp.ganpatuniversity.ac.in
Article In Press
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPRT ISSUE

January - March 6 [1] 2014

Click to download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
PIPPHARMACON & IJPR 2018

PIPPHARMACON & IJPR 2018

Click to download
 

Article Detail

Label
Label
Cytotoxic potential of the crude solvent extract of Botryodiplodia theobromae – an endophytic fungi isolated from Catharanthus roseus.

Author: VARDHANA J, KATHIRAVAN GOVINDARAJAN
Abstract: Endophytes are microbes that colonize living, internal tissues of plants without causing any immediate negative effects. A large number of secondary metabolites have been extracted, isolated and characterized from endophytic microbes. In the present study, the medicinal plant Catharanthus roseus is used for the endophtyes isolation. The aim of this study is to extract secondary metabolites from Botryodiplodia theobromae, an endophytic fungi, isolated from Catharanthus roseus and to check the anti cancer potential of the solvent extract in MCF-7 and A549 cancer cell lines. The assay clearly evidenced that at the comcentration of 100 µl of the sample, there was a potent cytotoxic effect in the cancer cell lines. This study proves that active secondary metabolites can be extracted from endophytes, which proves to be a cost effective method for medical applications.
Keyword: Endophytes, Botryodiplodia theobromae, MCF-7, A549, Cytotoxicity, Secondary metabolites.
Download: Request For Article
 












USER LOGIN


Username
Password
Login | Register
AICTE INTERNATIONAL CONFERENCE

AICTE Sponsored International Conference on Challenges, Opportunities and Newer Directions of Pharmacovigilance and Clinical Research in India

Download Brochure


For More Detail Visit www.pippharmacon.org
News & Events
hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus
Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477