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Antimicrobial Activity of Moringa oleifera Leaves Extracts against Isolated Human Dental Pathogens
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| Author:
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KEVINA YANASEGARAN, ANITA GNANA KUMARI ANPUMONI VIMALA, ANANDARAJAGOPAL KALUSALINGAM
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| Abstract:
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Dental caries are considered as one of the key oral in health issues. Synthetic drugs and antibiotics have side effects and can develop resistance. Moringa oleifera is a plant with enormous established pharmaceutical properties. The present study was designed to evaluate the antimicrobial activity of M. oleifera leaves against the isolated human dental pathogens. The water and ethanolic extracts of M. oleifera leaves were obtained by cold maceration method. The isolated dental pathogens are Streptococcus mutans, Lactobacillus acidophilus, Klebsiella pneumoniae and Candida albicans. Cup plate method was used to evaluate the antimicrobial activity of water and ethanolic extracts of M. oleifera leaves against the isolated microbes. The water extract of M. oleifera leaves was active against S. mutans and C. albicans. The ethanolic extract of M. oleifera leaves was active against all the 4 strains (S. mutans, Lactobacillus, K. pneumoniae and C. albicans). Both water and ethanolic extracts of -M. oleifera leaves shows maximum antimicrobial activity against S. mutans with diameter of inhibition zones 25.7 mm and 22.3 mm respectively, The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of water and ethanolic extracts of M. oleifera against S. mutans were found to be 25 mg/ml and 50 mg/ml respectively. Further studies are required to evaluate the safety and therapeutic efficacy of M. oleifera leaves in combating dental caries.
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| Keyword:
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Moringa oleifera, leaves, ethanolic extract, water extracts, dental pathogens, antimicrobial
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| EOI:
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| DOI:
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