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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

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Article In Press
Biomechanical/biochemical factors contributing to cardiac fibrosis in the heart and engineered cardiac tissue
THE ASSOCIATION AND LINKGAGE OF VARIOUS RETROVIRUSES AND ITS PROGRESSION TOWARDS NEURODEGENERATION
Architecture of Viral RNA Helicases; HCV helicase as Antiviral Target
GC-MS analysis of rhizome extract by Cold maceration of Curcuma amada Roxb.
Development and Evaluation of Febuxostat Sublingual Tablet Formulation
Development and Evaluation of Febuxostat Sublingual Tablet Formulation
A comparative study of adaptogenic effect of Withania somnifera with Mifepristone (a GR antagonist) on chronic stress - induced perturbations in glucose metabolism
In Vitro Anticancer Activity Of Leaves Of Rumex Vesicarius Linn And Symplocos Racemosa Roxb By Trypan Blue Method
PREPARATION AND INVITRO CHARACTERISATION OF ANTIBACTERIAL NANOCAPSULES
Cytotoxic potential of the crude solvent extract of Botryodiplodia theobromae – an endophytic fungi isolated from Catharanthus roseus.
12
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January - March 6 [1] 2014

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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Article Detail

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Antimicrobial Activity of Moringa oleifera Leaves Extracts against Isolated Human Dental Pathogens

Author: KEVINA YANASEGARAN, ANITA GNANA KUMARI ANPUMONI VIMALA, ANANDARAJAGOPAL KALUSALINGAM
Abstract: Dental caries are considered as one of the key oral in health issues. Synthetic drugs and antibiotics have side effects and can develop resistance. Moringa oleifera is a plant with enormous established pharmaceutical properties. The present study was designed to evaluate the antimicrobial activity of M. oleifera leaves against the isolated human dental pathogens. The water and ethanolic extracts of M. oleifera leaves were obtained by cold maceration method. The isolated dental pathogens are Streptococcus mutans, Lactobacillus acidophilus, Klebsiella pneumoniae and Candida albicans. Cup plate method was used to evaluate the antimicrobial activity of water and ethanolic extracts of M. oleifera leaves against the isolated microbes. The water extract of M. oleifera leaves was active against S. mutans and C. albicans. The ethanolic extract of M. oleifera leaves was active against all the 4 strains (S. mutans, Lactobacillus, K. pneumoniae and C. albicans). Both water and ethanolic extracts of -M. oleifera leaves shows maximum antimicrobial activity against S. mutans with diameter of inhibition zones 25.7 mm and 22.3 mm respectively, The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of water and ethanolic extracts of M. oleifera against S. mutans were found to be 25 mg/ml and 50 mg/ml respectively. Further studies are required to evaluate the safety and therapeutic efficacy of M. oleifera leaves in combating dental caries.
Keyword: Moringa oleifera, leaves, ethanolic extract, water extracts, dental pathogens, antimicrobial
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22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit https://ncsp.ganpatuniversity.ac.in
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)