IJPR  artciles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 1.55 (2012 - 2016). 

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Antimicrobial Activity of Moringa oleifera Leaves Extracts against Isolated Human Dental Pathogens

Author: KEVINA YANASEGARAN, ANITA GNANA KUMARI ANPUMONI VIMALA, ANANDARAJAGOPAL KALUSALINGAM
Abstract: Dental caries are considered as one of the key oral in health issues. Synthetic drugs and antibiotics have side effects and can develop resistance. Moringa oleifera is a plant with enormous established pharmaceutical properties. The present study was designed to evaluate the antimicrobial activity of M. oleifera leaves against the isolated human dental pathogens. The water and ethanolic extracts of M. oleifera leaves were obtained by cold maceration method. The isolated dental pathogens are Streptococcus mutans, Lactobacillus acidophilus, Klebsiella pneumoniae and Candida albicans. Cup plate method was used to evaluate the antimicrobial activity of water and ethanolic extracts of M. oleifera leaves against the isolated microbes. The water extract of M. oleifera leaves was active against S. mutans and C. albicans. The ethanolic extract of M. oleifera leaves was active against all the 4 strains (S. mutans, Lactobacillus, K. pneumoniae and C. albicans). Both water and ethanolic extracts of -M. oleifera leaves shows maximum antimicrobial activity against S. mutans with diameter of inhibition zones 25.7 mm and 22.3 mm respectively, The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of water and ethanolic extracts of M. oleifera against S. mutans were found to be 25 mg/ml and 50 mg/ml respectively. Further studies are required to evaluate the safety and therapeutic efficacy of M. oleifera leaves in combating dental caries.
Keyword: Moringa oleifera, leaves, ethanolic extract, water extracts, dental pathogens, antimicrobial
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News & Events

2017: 6.457
2016: 5.999
2015: 5.406
2014: 5.099

CiteScore 2016 -  0.09

SJR 2016 - 0.111

SNIP 2016 - 0.055

Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)