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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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In Vitro Anticancer Activity Of Leaves Of Rumex Vesicarius Linn And Symplocos Racemosa Roxb By Trypan Blue Method

Author: MD JAVEED MANURE, N.S NAIKWADE
Abstract: Abstract: Objective: The objective of present study to evaluate anticancer activity of leaves of Rumex vesicarius Linn and Symplocos racemosa Roxb. Methods: In this study Cytotoxicity was assayed by Trypan blue dye exclusion method, different extracts of leaves of plant Rumex vesicarius Linn. & Symplocos racemosa Roxb were found to be cytotoxic to HT-29 and PC-3 cell line. Result: Different extracts of leaves of plant Rumex vesicarius Linn. and Symplocos racemosa Roxb were showed significant (P<0.001) cytotoxic effect on HT-29 and PC-3 cell line in a dose dependent manner. Conclusion: The study demonstrated that all the extracts of Rumex vesicarius Linn and Symplocos racemosa Roxb shows significant Cytotoxic effect on HT-29 and PC-3 cell line in dose dependent manner.
Keyword: Rumex vesicarius Linn, Symplocos racemosa Roxb, Trypan blue exclusion assay.
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