IJPR  artciles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 1.55 (2012 - 2016). 

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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IJPRT ISSUE

January - March 6 [1] 2014

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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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PIPPHARMACON & IJPR 2018

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Exploring Anticancer Potential of ZnO(NPs) in DMBA-Croton oil Induced Skin Carcinogenesis

Author: DEEPIKA JHANWAR, PROF. JAIMALA SHARMA
Abstract: This study was conducted to evaluate the antitumor effect of cationic ZnO nanoparticles (NPs) on 7, 12– Dimethylbenz(a)anthracene (DMBA) induced skin carcinogenesis in male Swiss albino mice.DMBA was applied on the shaved back of mice for the induction of tumor and then left for two weeks, after that Croton oil was applied thrice a week. In experimental mice ZnO (NPs) were applied along with Croton oil application and continued upto next 14 weeks. The effect of ZnO(NPs) on tumor growth was studied by Catalase (Cat) activity, Super oxide dismutase (SOD) activity, Reduced glutathione content(GSH),Vitamin C (Vit-C) content, Lipid peroxidation (LPO) and Total protein content in the skin. The SOD and catalase activities were found to be higher in the experimental animals (ZnO treated) as compared to only carcinogen treated positive control mice. The differences in the values of the results of experimental groups were statistically analyzed which were significant in comparison to the control group. The LPO in experimental groups significantly decreased as compared to the carcinogen treated control group. The GSH,vitamin C and total protein contents were comparatively higher in the ZnO(NPs) treated group. The results indicate chemopreventive and thearapeutic effects of ZnO (NPs) treatment.
Keyword: DMBA, ZnO nanoparticles, Lipid peroxidation, Catalase, Superoxide dismutase and Vitamin C.
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News & Events

2017: 6.457
2016: 5.999
2015: 5.406
2014: 5.099

CiteScore 2016 -  0.09

SJR 2016 - 0.111

SNIP 2016 - 0.055

Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)