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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Explore the Antimicrobial Potential from Organic Solvents of Brown Seaweed extracts (Sargassum longifolium) alleviating to pharmaceuticals

Author: RAJESHKUMAR S, M. PONNANIKAJAMIDEEN, M. MALINI, C. MALARKODI
Abstract: Marine macro algae sargassam’s are commonly referred to as brown seaweeds. Commercially and continuously the pharmaceuticals industries are rapidly growing because always demand for new drug discovery is encouraged. Since brown seaweeds have ample source of bioactive compounds of primary or secondary metabolites. These potential bioactive compounds interest to improve the pharmaceuticals industry. This present study was investigated to explore the antimicrobial and antifungal activity of the organic solvents of the brown seaweed Sargassum. Phytochemical analysis of Brown seaweeds of Sargassam longifolium with six different organic solvents was analysed. The solvents like Dimethyl Sulfoxide (DMSO), Benzene, Acetic acid, hexane, Di Ethyl ether and Chloroform has the extraction of phytochemical constituents. Among the six solvents Dimethyl Sulfoxide (DMSO) extract showed maximum number of phytochemical constituents and antimicrobial and antifungal activity when compared to other five solvent extracts.The responsible functional groups in the solvent extract were identified by FTIR. These results statements be a necessary (or) recommended that the species of brown seaweeds (Sargassum longifolium) having a potential capacity as a source of antimicrobial compounds, which makes them interesting for screening for natural and highly bioactive secondary metabolites products it may leads to development of new pharmaceutical agents.
Keyword: Sargassum longifolium, Brown seaweed, Phytochemicals, Antimicrobial Assay, FTIR
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