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A Convenient strategy for the synthesis and characterisation of Biologically important Schiff bases encompassing Naphtho[2,1-b]thiophene carboxylic Acid
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| Author:
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VEENA KOTABAGI, SHASHIKALA DEVI K
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| Abstract:
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Abstract
The desired synthesis of target molecules has been accomplished, in the following steps.
Thionation of ethylnaphtho[2,1-b]furan-2-carboxylate(1)produced ethyl naphtho[2,1- b]thiophene-2 carboxylate(2).Nitration of the ester resulted in the formation of ethyl-8-nitronaphtho [2,1-b] thiophene-2-caboxylate(3).Hydrolysis of the nitro ester yielded corresponding carboxylic acid(4).
Reduction of this compound produced 8-aminonaphtho [2,1-b]thiophene-2-carboxylicacid(5).
Reaction of 8-aminonaphtho[2,1-b]thiophene-2-carboxylic acid with different aromatic aldehydes produced the title compounds(6a-e).
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| Keyword:
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Thionation, Naphthofuarn,Naphthothiophene
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| EOI:
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| DOI:
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-
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| Download:
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