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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

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Impact Factor: 1.46

Total Publications: 326

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A Convenient strategy for the synthesis and characterisation of Biologically important Schiff bases encompassing Naphtho[2,1-b]thiophene carboxylic Acid

Author: VEENA KOTABAGI, SHASHIKALA DEVI K
Abstract: Abstract The desired synthesis of target molecules has been accomplished, in the following steps. Thionation of ethylnaphtho[2,1-b]furan-2-carboxylate(1)produced ethyl naphtho[2,1- b]thiophene-2 carboxylate(2).Nitration of the ester resulted in the formation of ethyl-8-nitronaphtho [2,1-b] thiophene-2-caboxylate(3).Hydrolysis of the nitro ester yielded corresponding carboxylic acid(4). Reduction of this compound produced 8-aminonaphtho [2,1-b]thiophene-2-carboxylicacid(5). Reaction of 8-aminonaphtho[2,1-b]thiophene-2-carboxylic acid with different aromatic aldehydes produced the title compounds(6a-e).
Keyword: Thionation, Naphthofuarn,Naphthothiophene
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477