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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Diabetes and Management of Lipid Level Following PCI in Acute Coronary Syndrome Patients.

Author: UPLOADED BY-ADMIN, PATEL JP, PARIKH KH, PATEL JC, KAREN HD, ANAND IS, SHAH JS
Abstract: Elevated low-density lipoprotein (LDL) cholesterol is a major cause of coronary heart disease. Although national guidelines for cholesterol management have existed since 1988, many patients with elevated cholesterol do not achieve their target cholesterol with treatment. Our aim was to identify the rate of lipid control. It was observational cohort study of 133 patients who underwent Percutaneous Coronary Intervention, who were investigated for their lipid profile at 30±7 days. The presence of diabetes and hypertension were added as a risk factor. The patients mean age, diabetics and hypertensive were 55.73yrs, 45(33.83%), 61(45.86%) respectively. Monotherapy was prescribed in 99(74.43%) patients, while 32(24.07%) were treated with combination of therapy. Only 2(1.50%) patients were not given any hypolipidemic therapy. The dose of statin 80 mg, 40mg and 10mg were given to 91(68.42%), 35(26.31%) and 4(3.0%) patients respectively. The statin was not given to 3(1.25%) patients. Low Density Lipoprotein Cholesterol (LDL-C) <70mg/dl in 111(83.45%) patients. While High Density Lipoprotein Cholesterol (HDL-C) >40mg/dl in 48(36.09%), Serum Triglyceride <150mg/dl in 110(82.70%), serum cholesterol was less than 160mg/dl in 124(93.23%) and Very Low density Lipoprotein (VLDL) was found less than 30mg/dl in 110(82.70%) patients. Acceptable lipid profile control was achieved and the majority of Coronary Heart Disease (CHD) patients were on lipid lowering therapy in high dose, which indicate current prescription guidelines is followed but present therapy seems to be inadequate in raising HDL-cholesterol.
Keyword: Elevated low-density lipoprotein (LDL) cholesterol is a major cause of coronary heart
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