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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Studies on Antimicrobial Potentials of Aerva lanata Fractions

Author: BASAVARAJ DINNIMATH, S S JALALPURE
Abstract: The aim of this study is to test the efficacy of different fractions of Aerva lanata extract for their antimicrobial activity and analyze the influence of fractions on the virulent factors of microorganisms. The whole plant Aerva lanata ( L) Juss.Ex. Schlt, commonly known as Pashanabheda used by various Ayurvedic physicians for various diseased conditions traditionally. As this plant is widely available in western ghats and no scientific reports on the antimicrobial potency of the plant fraction/s reported till date, we have conducted this study with an objective that the results will enlarge the existing knowledge. In this study the whole plant was subjected for extraction with hydroalcohol followed by fractionation with different solvents based on their polarities. Urolithiasis is found to be one among the top five critical conditions responsible for urinary tract infections worldwide and as this plant is used as Pashanabheda traditionally, we are aimed at identifying the antimicrobial potency of this plant which shall help to substantiate the traditional claims of this plant in nurolithiasis treatment. We found that different fractions of this plant have produced promising antimicrobial results against E.coli, Bacillus sp, S.aureus. Proteus sp.
Keyword: lanata , antimicrobial activity, Pashanabheda, urinary tract infections
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