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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antimicrobial Activity of Methanolic and Water Extracts of Alchornea cordifolia Leaf

Author: UPLOADED BY-ADMIN, SARAVANAN D, PADMAVATHY J, PARIMALA M.J, APARNA LAKSHMI I, PRAVEEN KUMAR C
Abstract: The fight against pathogens is becoming a continuous exercise due to development of resistance by the organisms. The emergence of researches on the antimicrobial properties of plant parts may bring solutions to these problems. The antimicrobial activities of the methanolic extract (ME) and water extract (WE) of Alchornea cordifolia leaf against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Candida albicans were investigated. Agar diffusion and agar dilution methods were used for the antimicrobial screening. The extracts showed broad spectrum activity against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, fungi/yeast - Candida albicans with diameter of zones of inhibition ranging from 11.0 to 30.0 mm. The Minimum Inhibitory Concentrations (M.I.C.)/Minimum Bactericidal/Fungicidal Concentrations (M.B.C/M.F.C.) of the extracts against the organisms was found to fall between1.25–20.0 mg/ml. The observed antimicrobial activities in this study proved that the leaf extracts of Alchornea cordifolia support the forcloric claims of the use of Alchornea cordifolia in the treatment of ailments such as wound dressing.
Keyword: Alchornea cordifolia, Water extract, Methanolic extract, Susceptibility, Antimicrobial activity.
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