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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Characterization of Cashew Nut Gum as a Binder in Tablet Formulation

Author: UPLOADED BY-ADMIN, SARIKA M. WAIRKAR, ANSHUMAN A. AMBIKE, ANANT R.PARADKAR
Abstract: Cashew nut gum, an exudate from Anarcardium occidentale L. trees, was evaluated as a pharmaceutical binder. Granules of paracetamol, a poorly compressible drug and lactose were prepared with varying binder concentration by wet granulation. Characterization of granules on the basis of micromeritic properties, mechanical properties, compressibility and compactability was carried out in comparison with standard pharmaceutical binders (gelatin and PVP). Cashew nut gum as a binder yielded large and uniform granules with good flow properties, compressibility and compactability.
Keyword: Cashew nut gum, binder, friability of granules, compressibility, compactability
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