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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Association of Plasma Ascorbic Acid Levels in South Indian Asthma Patients

Author: UPLOADED BY-ADMIN, RAJALAKSHMI A G, SUDHA S
Abstract: Reactive Oxygen Species induced bronchial abnormalities may have important consequences in asthma. Vitamin C is an important antioxidant known to quench the reactive oxygen species. This study aims to evaluate the association of vitamin C as an independent risk factor for bronchial asthma. Blood samples of 45 bronchial asthma patients and 45 controls were analyzed for plasma ascorbic acid level and compared with healthy controls. The results showed that plasma ascorbic acid deficiency exist at low levels in asthmatics. There was a major difference between the patients and control groups in mean ascorbic acid level. Plasma ascorbic acid levels were significantly decreased in asthmatics (P< 0.05) with balance shifting toward increased oxidative stress, which neutralizes free radical and protects the bronchial tissues from oxidative injury.
Keyword: Asthma, Ascorbic acid, Plasma, Reactive Oxygen Species.
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