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Association of Plasma Ascorbic Acid Levels in South Indian Asthma Patients
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| Author:
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UPLOADED BY-ADMIN, RAJALAKSHMI A G, SUDHA S
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| Abstract:
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Reactive Oxygen Species induced bronchial abnormalities may have important consequences in asthma. Vitamin C is
an important antioxidant known to quench the reactive oxygen species. This study aims to evaluate the association of vitamin C
as an independent risk factor for bronchial asthma. Blood samples of 45 bronchial asthma patients and 45 controls were analyzed
for plasma ascorbic acid level and compared with healthy controls. The results showed that plasma ascorbic acid deficiency exist
at low levels in asthmatics. There was a major difference between the patients and control groups in mean ascorbic acid level.
Plasma ascorbic acid levels were significantly decreased in asthmatics (P< 0.05) with balance shifting toward increased oxidative
stress, which neutralizes free radical and protects the bronchial tissues from oxidative injury.
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| Keyword:
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Asthma, Ascorbic acid, Plasma, Reactive Oxygen Species.
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| EOI:
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| DOI:
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| Download:
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