Effects of the Extracts of Aristolochia and Tylophora species on Plasmdoium falciparum In vitro.
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Author:
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UPLOADED BY-ADMIN, D. RANA,, D.S. MEHTA, K.R. DESAI, H.N. HIGHLAND, L.B. GEORGE.
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Abstract:
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Till to-date of all the known antimalarials in the market which reduces the malaria burden are obtained from the various
plant extracts. Antimalarial drugs from the plant extracts have proven their worth more efficient in suppressing malaria as
compared to synthesized drug. With a number of new cases of infections and deaths, malaria continues to be an enormous
global health challenge. Malaria is one of the major health problems that needs attention of scientists involved in drug
discovery to find out new novel compounds with high drug efficacy, safety and low cost against Plasmodium species that are
resistant to the existing drug molecules. The present study was to investigate the in vitro efficacy of the crude extracts of two
plants viz., Aristolochia bracteolata Lam. (Aristolochiaceae) and Tylophora indica (Burn.F) R.Br. (Asclepidaceae). The
aqueous and some of the non-polar solvent extracts of these plants had shown very promising antiplasmodial activity.
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Keyword:
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Plasmodium species, Aristolochia bracteolata, Tylophora indica,
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EOI:
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DOI:
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