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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Effects of the Extracts of Aristolochia and Tylophora species on Plasmdoium falciparum In vitro.

Author: UPLOADED BY-ADMIN, D. RANA,, D.S. MEHTA, K.R. DESAI, H.N. HIGHLAND, L.B. GEORGE.
Abstract: Till to-date of all the known antimalarials in the market which reduces the malaria burden are obtained from the various plant extracts. Antimalarial drugs from the plant extracts have proven their worth more efficient in suppressing malaria as compared to synthesized drug. With a number of new cases of infections and deaths, malaria continues to be an enormous global health challenge. Malaria is one of the major health problems that needs attention of scientists involved in drug discovery to find out new novel compounds with high drug efficacy, safety and low cost against Plasmodium species that are resistant to the existing drug molecules. The present study was to investigate the in vitro efficacy of the crude extracts of two plants viz., Aristolochia bracteolata Lam. (Aristolochiaceae) and Tylophora indica (Burn.F) R.Br. (Asclepidaceae). The aqueous and some of the non-polar solvent extracts of these plants had shown very promising antiplasmodial activity.
Keyword: Plasmodium species, Aristolochia bracteolata, Tylophora indica,
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