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Development and Evaluation of Terbutaline SulphateTransdermal Film
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| Author:
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UPLOADED BY-ADMIN, PATTANAYAK DHARMAJIT, DAS SAUMYA, SAHU NIGAM PRASAD
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| Abstract:
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The present investigation was aimed to formulate transdermal films incorporating Terbutaline Sulphate, a drug used in
the treatment and management of Asthma. The two different polymers like ethyl cellulose and hydroxyl propyl methyl
cellulose were used in varying ratios. Polyvinyl alcohol is used as backing membrane. The polymeric films were evaluated
for their physical properties like physical appearance, thickness, drug content, moisture content, folding endurance, in-vitro
evaluation and stability studies. The FT-IR spectra analysis of physical mixture in ratio 1:1 containing drug and polymer
showed no shift in peak hence no interactions. Formulation TTS2 showed satisfactory results and hence was optimised.
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| Keyword:
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Terbutaline Sulphate, ethyl cellulose (EC), hydroxyl propyl methyl cellulose (HPMC)
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| EOI:
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| DOI:
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